A Case Report on Clindamycin Induced Pain and Swelling Over Right Limb

Abstract

Clindamycin is a lincosamide antibiotic that inhibits bacterial protein synthesis. It is approved for the treatment of anaerobic, streptococcal, and staphylococcal infections. Adverse effects of clindamycin include diarrhea, pseudomembranous colitis, metallic taste in the mouth, transient elevations in liver transaminases, granulocytopenia, and thrombocytopenia. A 33-year-old female with cervicitis was hospitalized in the obstetrics and gynecology department of a tertiary care teaching hospital. Inj. Clindamycin (600mg/4mL) was administered to the patient on 18/1/2020, and then the patient developed pain and swelling over the right limb. Clindamycin was withdrawn. Meanwhile, the patient was administered Inj. Avil 2 mL (Pheniramine Maleate) IV stat, Inj. Hydrocort (Hydrocortisone) IV stat and 100ml IV infusion Normal Saline was given as treatment. Pain and swelling of the right limb are a rare presentation of adverse drug reaction produced by clindamycin.